That depends on your mac OS version.  Preferably, you should open PTO in Private mode, which avoids a lot of the common issues.  Clear your cache, restart your browser, and restart your machine if necessary.  This is the normal routine that solves 99.9% of the problems.

https://proconnect.intuit.com/community/help-articles/help/system-requirements-for-proconnect-tax-on...

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