When I got the Error 10250, I was still able to print to PDF, but I couldnt print to the printer.....I powered off (not just a restart) both computer and printer, then powered them both back up and the error didnt come back for me.

This is the ProSeries support article for that error, in case a cold boot of both computer and printer doesnt work for you.

https://proconnect.intuit.com/community/help-articles/help/attempting-to-print-in-proseries-products...