Hi @RichieA Thanks for posting in the community and sharing what is happening when trying to open ProSeries on your virtual machine. We would try the following:

1. Restart the Virtual Machine, try again.
2. If still happening, go to the Windows Start Menu>All>Scroll to ProSeries 2025 folder and expand it. 
3. You will see Tools - Connected Customer and Repair Updates. Try running the Connected Customer first and follow the on screen prompts.
4.  If still having an issue, try the Repair Updates. 

Let us know if this helps. 

Thanks! 

Kathi