I had some file corruptions when one (or more) of the Proseries auto updates updated our computers automatically overnight and clashed with other software scheduled to update overnight at the same time using up all the memory on the workstations. In any case, if you are allowing Proseries to automatically update your computer then you should be ok. My firm needed to manually update as there are not enough overnight hours to update scheduled software updates.

Auto updates are not a problem but to check that you have all the updates, you can go to Update, Refresh Updates and let Proseries check that all the latest updates are applied. It simply checks the updates on your computer against the auto updates they have issued and verifies nothing was missed. Run it only once a day because by refreshing it goes through the whole process again and again and it is misleading because it looks like it is updating your Proseries every time you refresh when in fact all it is doing is checking yours against theirs. If you are on Auto updates and you click on "update installed products" it never seems to find any updates, at least that is what I found on our system. 

If you are manually updating your computer, then you do an "update installed products" once a day, or at least that is what my staff are told to do, update each morning when logging on Proseries. 

To change from auto updates to manual updates you go under Updates then "background updates" and click on "Deactivate background updates". You can go back to Auto by "Activate background updates".