Rebooting your computer didn't help?

The same clients each time? Do they have anything in common that you can think of?
You may want to download the ProSeries Tools Hub and see if any of the repair options in there help at all.
https://proconnect.intuit.com/community/system-responses/help/fix-common-problems-and-errors-with-th...

I had to go into Tools > Auto Calculation and turn it off and back on and that helped.  Not sure if yours is the same problem.

Yes, it is the same clients every time

Thanks, where is Auto Calculations under Tools...I do not see it as an option.

Never mind, I found it.  I'll see if that works.