We do use the direct deposit feature for payroll checks in EasyACCT, but not A/P, so I can only speak from payroll experience. Have you reviewed the information in the Help Menu for how to process direct deposit transactions?  That is a good starting point. 

As for uploading file to the bank, every bank is different - as well as their fees.  Some charge a monthly fee, some charge a per item fee, and some charge both.  You will have to contact the bank directly and ask what they charge. Also, each bank should be able to walk you thru their process for uploading the NACHA file - again it differs for each bank.  You will also need to ask them for their NACHA spec sheet before you process any transactions so that you can make sure the file EasyACCT produces matches their specifications for processing direct deposits.  

Once you have everything set up, processing the files is a breeze!  

For what it's worth, in our experience, the local banks are much more user friendly to deal with than the national banks.