Marieclinton2010,

For 1099 efiling with the IRS FIRE (Filing Information Returns Electronically) you need to do is establish a TCC number with the IRS.  You need to file out a Form 4419; once you receive that confirmation back (which does take up to 4 weeks), you will be able to setup your online access on the https://fire.irs.gov/ site.

For the W2s, you will need to setup and account with the BSO (Business Services Online) Social Security online site.  This part can be confusing but if you can any questions their help line is rather good (800-772-6270). 

Unfortunately I am not setup to efile 941s or 940s yet so I'm not positive about that process.  I do hope this helps.