If this may help, my firm found a work-a-round by using a computer with a fresh clean install of lacerte to e-file tax returns. No issues since. Almost all of our primary computers we used had some form of error whether it be backing up after editing a client's tax data, or restoring clients. Also any clients that experience the lacerte error when backing up are immediately "broken" and we have not found a fix other then going back to a prior version of the client that did not error. 

For our primary computers, it didn't matter what schedule we made changes to, even changing a number by one digit caused it to not be able to back-up without erroring. 

I suggest using a desktop with a clean install of lacerte to edit any client's tax data and e-file until Lacerte issues out a fix.