I actually don't know, but this article says you can and makes a decent case for it.

https://www.hcvt.com/alert-Opportunity-Zones

As far as how you enter it into Lacerte, I don't know for certain, but I'd imagine you still use Screen 17 (because there's nothing for it on Screen 12) to do *only* the QOZ line entry (normally you input two entries: one reg disposition line and another to defer it to QOZ - Lacerte has Knowledge Base articles you can look up on this).  And then it should net out on the bottom of Sch D.

I haven't had any clients want to do this or have big Cap Gains to be eligible, but it sure looks cool.  Good luck!